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Amaryl MV (glimepiride, metformin, voglibose) is a type 2 diabetes treatment containing three active ingredients in one tablet, ideal for patients for whom one or two medications do not produce sufficient results.

The three active ingredients in Amaryl MV are:

  • Glimepiride promotes insulin production by the pancreas, lowering blood sugar as the new, additional insulin converts it to energy or stores it in tissues.
  • Metformin lowers blood sugar by reducing its production in the liver, inhibiting glucose absorption, and increasing glucose uptake by muscle and fat.
  • Voglibose inhibits the digestion of carbohydrates and delays the absorption of glucose, preventing post-meal surges of glucose.

The above three products can be bought independently, but many patients prefer to buy Amaryl MV for convenience of administration. Cost is also often lower when buying combined tablets.

This product should not be confused with Amaryl MP, which has a similar name---and is in fact similar to Amaryl MV---but has a different ingredient, containing pioglitazone instead of voglibose.

In type 1 diabetes, in which the pancreas is unable to produce significant insulin, this medication will not provide any benefit; these patients should not buy Amaryl MV.

Taking Amaryl MV

Patients who buy Amaryl MV will receive tablets, typically taken just once per day with a meal. Most patients take them in the morning with breakfast. Food helps the medications work well while reducing gastrointestinal side effects, which metformin in particular is somewhat notorious for. A full beverage is also recommended.

Most patients taking three antidiabetic treatments have already tried one or two, and found them to be insufficient. It is rare that patients are started on three medications at first, though it does sometimes happen.

Patients taking all three of the same medications found in Amaryl MV, but rather than taking each individually are switching to Amaryl MV, should try to match the doses as much as possible. All other patients---those new to one or more of the medications in Amaryl MV---are typically started on low doses unless explicitly instructed otherwise by a doctor.

In other words, most patients:

  • Start with low doses of 1 mg/500 mg/0.2 mg glimepiride/metformin/voglibose.
  • Take this dose for one or two weeks; it takes this long for maximum benefit to be seen.
  • After one or two weeks, dosage may be increased, if needed, in small increments every two weeks.
  • Blood sugar should be monitored closely at the start of treatment and following any dosage adjustments.

Note that taking multiple Amaryl MV tablets provides the same benefit as taking a single higher-dose tablet; for example, two 1 mg/500 mg/0.2 mg tablets is the same as taking a single 2 mg/1000 mg/0.4 mg tablet. It may not be advisable to increase dosage by so much, though; doctor involvement is important in determining dosage levels. Doctor instructions are individualized for each patient and should be followed.

Lifestyle Changes

Patients given a prescription to buy Amaryl MV will almost certainly be advised to make lifestyle changes, such as:

  • Reach and maintain a healthy weight
  • Get regular exercise
  • Control blood sugar
  • Control blood cholesterol
  • Quit smoking
  • Avoid stress as much as possible

These changes often sound---and are---unpleasant at first. However, they're very much worth complying with; as a patient becomes used to them they're no longer unpleasant, the patient will feel better, and in the vast majority of cases lifestyle changes are the only way to minimize or eliminate dependency on medications to manage blood sugar.

Rarely some patients make all recommended changes and still experience little change in type 2 diabetes. These patients---as well as those disinclined to make such changes---will most likely need to buy Amaryl MV, or similar medications, indefinitely, possibly for the remainder of life.

Potential Complications

The three active ingredients in Amaryl MV put patients at an increased risk of hypoglycemia, or low blood sugar. Close monitoring of blood sugar often prevents serious issues, but they can happen even to the most attentive patient and may require emergency medical attention. All patients who buy Amaryl MV should be aware of symptoms and how to manage them. The prescribing doctor should make this information available, and there is also an abundance of information online.

Most side effects are mild and transient, meaning they typically stop occurring in the first few weeks of treatment. Rarely more serious side effects develop, which warrant attention by a doctor, including:

  • Severe gastrointestinal pain
  • Severe itching
  • Chest pain
  • Hypoglycemia

Other side effects may develop which are not detectable by the patient. These include:

  • Low red or white blood cell counts
  • Low blood platelets
  • Altered kidney or liver enzymes
  • Low sodium
  • Lowered immunity
  • Impaired bile flow

A doctor should periodically screen for the above. Medical staff should be made aware that Amaryl MV is being taken prior to performing laboratory tests for unrelated reasons.

Interactions with other medications, including over-the-counter varieties and recreational drugs, are associated with Amaryl MV. The prescribing doctor should be made aware of all medications taken during treatment, and recreational drugs---such as alcohol---should not be used in excess.

When It Comes To Health, We Deliver

If you need to buy Amaryl MV, you've come to the right place---New Zealand's oldest and most-trusted online pharmacy. Kiwi Drug delivers only authentic, safe medications from authorized manufacturers. We're backed by an international network of brick & mortar pharmacies in operation for decades, and subject to the same regulatory oversight as our real-world counterparts. Our low prices are the result of the low overhead of our online storefront---not cutting quality.

Clients will need a prescription to buy Amaryl MV. If you don't have one, you're welcome to take advantage of our online doctor services for no additional charge. Simply add the product to your cart, initiate checkout, and answer the questions about your medical history and other medications being taken to see if you qualify.

Patients who already have a prescription to buy Amaryl MV will be given options to transfer it to us after completing checkout.

We're always here to help with any questions you may have about this or any of our products.

**Important note for patrons: The information on this page is not official label or safety information as written by the manufacturer or reviewed by the FDA. We only list for sale and refer orders to our affiliates for medications approved in the country where they are licensed, and any product requiring a prescription must be sold under the direction of a licensed physician.
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